|
|
Monoclonal Antibody
-
Definitions of Monoclonal Antibody on the Web - Highly specific, purified antibody that is derived from only one clone of cells and recognizes only one antigen.
-
Monoclonal Antibodies - Introduction, The procedure, Uses for monoclonal antibodies, Some monoclonal antibodies that have been introduced into human medicine, Problems with monoclonal therapy, Looking ahead.
-
Recombinant Monoclonal Antibodies - The need to overcome the immunogenicity problem of rodent antibodies in clinical practise has resulted in a plethora of strategies to isolate human antibodies. If human antibodies are to be used, then one would like to understand the basis by which different isotypes interact with host effector systems, and, if possible, improve on nature by engineering in desirable modifications.
-
The Mouse in Science: Monoclonal Antibodies - In 1975, Kohler and Milstein first fused lymphocytes to produce a cell line which was both immortal and a producer of specific antibodies. The two scientists were awarded the Nobel Prize for Medicine in 1984 for the development of this "hybridoma." The value of hybridomas to the field was not truly appreciated until about 1987, when MAbs were regularly produced in rodents for diagnostics.
-
Rabbit Monoclonal Antibodies (RabMAb’s): The latest advance in Immunohistochemistry - Monoclonal antibodies have traditionally been produced in a mouse. Why a mouse? Because, as a host, it is cost effective, easy to manage, and truly a standard in many biotechnology applications.
-
General Outline of Producing a Rabbit Monoclonal Antibody - Epitomics has developed a unique and proprietary method for making monoclonal antibodies from rabbits rather than the conventional method of starting with mice.
-
Frequently Asked Questions (FAQs) on Rabbit Monoclonal Antibody - Q: What is a RabMab ? A: RabMab stands for Rabbit Monoclonal antibody.
-
Advantages and Disadvantages of Monoclonal Antibodies - Department of Pathology and Immunology Center for Immunology, Washington University School of Medicine.