Glioblastoma Multiforme (GBM) Markers




Glioblastoma multiforme (GBM), also known as grade 4 astrocytoma, is the most common and aggressive type of primary brain tumor, accounting for 52 percent of all primary brain tumor cases and 20% of all intracranial tumors. Despite being the most prevalent form of primary brain tumor, GBM's occur at only 2-3 cases per 100,000 people in Europe and North America.





  • telomerase activity and p53 mutations both play important roles in the multistep carcinogenesis of glioblastoma multiforme (GBMs). PMID: 11014540