Hematopoietic Progenitor/Stem Cell Markers








  • a novel marker for human hematopoietic stem and progenitor cells. PMID: 9389720

BAALC (Brain And Acute Leukemia, Cytoplasmic)


  • a cell surface marker for hematopoietic progenitor and stem cells. PMID: 7519070  

  • synthesized and expressed by early normal hematopoietic progenitor cells and by many acute leukemias, is a sensitive and relatively specific marker for neoplasms of vascular origin. PMID: 1712541

  • expressed at various levels on virtually all human hematopoietic progenitor cells (HPC), is a heavy glycosylated molecule with many different epitopes. PMID: 9704483

  • a marker of hematopoietic stem cells. PMID: 14634211

  • a hematopoietic progenitor cell antigen. PMID: 9720500


  • an adhesion molecule highly expressed by hematopoietic progenitor cells (HPC) and may be specifically involved in the regulation of HPC proliferation. PMID: 9368320, PMID: 8608215

  • expressed by many types of mature blood cells including T-lymphocytes, activated B-lymphocytes, neutrophils, monocytes, and platelets but not non-hemopoietic cells. PMID: 7858238

  • a mucin-like transmembrane sialoglycoprotein expressed on the surface of almost all hematopoietic cells. PMID: 10233884, PMID: 7605986


  • a marker for mature hematopoietic cells. PMID: 9472804

  • a transmembrane tyrosine phosphatase, is found on almost all nucleated hematopoietic cells and plays a crucial role in lymphocyte activation and differentiation. PMID: 8980254

  • present on all cells of the hematopoietic lineage. PMID: 12433683, PMID: 12799286


  • a new marker for normal hematopoietic progenitor and stem cells. PMID: 14768187

  • a surface molecule expressed on progenitors from hematopoietic and endothelial lineages. PMID: 16914572

  • a surface molecule expressed on progenitors from hematopoietic, endothelial, and neural lineages. PMID: 16269619

  • a plasma membrane marker found in several types of somatic stem cells, including hematopoietic and neural stem cells. PMID: 15917475

  • Although the biological function of Prominin-1 is not well understood, the AC133 epitope currently serves as a useful marker for the isolation of hematopoietic and endothelial progenitor cells. PMID: 15694831

  • an antigen expressed on hematopoietic progenitor cells and on some epithelial cells. PMID: 12133915

CDCP1 (CUB-domain-containing protein 1)

  • a novel transmembrane molecule that is expressed in metastatic colon and breast tumors as well as on the surface of hematopoietic stem cells. CDCP1 is not only a novel marker for immature hematopoietic progenitor cell subsets but also unique in its property to recognize cells with phenotypes reminiscent of MSC and NPC. PMID: 15153610

  • a novel marker for hematopoietic stem cells. PMID: 12799299



  • a CD34-like sialomucin, marks hematopoietic stem cells throughout development. PMID: 16314436

  • an early endothelial-specific antigen that is also expressed on putative hematopoietic progenitor cells. PMID: 11747076

Flk-2 (fetal liver kinase-2)

  • a marker in hematopoietic stem cell differentiation: a simple method to isolate long-term stem cells. PMID: 11724967


  • originally cloned from hematopoietic stem cell-enriched fetal liver and placenta and is believed by some investigators to play a role in the regulation of the hematopoietic stem cell. PMID: 9620281


  • has an important role in the expansion of early hematopoietic progenitors and in the generation of mature peripheral leukocytes. PMID: 10828034

Hemangiopoietin (HAPO)

  • a novel growth factor acting on both hematopoietic and endothelial cell lineages. PMID: 14976050


  • recognizes murine heat-stable antigen, a marker of antigen-presenting cells and developing hematopoietic cells. PMID: 8917116


  • expressed by cells of the hematopoietic branch of development. PMID: 3489673

Merocyanine 540 (MC540)

  • an impermeant fluorescent dye that binds preferentially to fluidlike domains of the cell membrane, is a differentiation marker on murine hematopoietic progenitor cells. PMID: 6602137

  • can be a useful probe for the isolation of primitive hematopoietic progenitor cells (HPC) from some hematopoietic tissues and may assist in monitoring structural changes in the phospholipid bilayer during proliferation and differentiation of HPC. PMID: 10349913

  • a useful molecular marker for blood cell differentiation and a basis for an effective purification of hematopoietic progenitor cells. PMID: 7327314


  • a novel hematopoietic-associated marker gene expressed in multipotent progenitor cells and up-regulated during myeloid differentiation. PMID: 10733104

  • localized to the nuclear envelope and to intracytoplasmic membranes, indicating that MYADM constitutes an integral membrane protein. PMID: 16172915


  • a neural and hematopoietic stem cell marker, is expressed in adult human differentiated cells and certain types of kidney cancer. PMID: 15558321


SCGF (stem cell growth factor)

  • a novel human growth factor for primitive hematopoietic progenitor cells. PMID: 9705843

  • a novel cytokine for primitive hematopoietic progenitor cells. PMID: 12900775

  • selectively produced by osseous and hematopoietic stromal cells, and can mediate their proliferative activity on primitive hematopoietic progenitor cells. PMID: 11920266


  • may function as a growth factor receptor on hematopoietic stem and/or progenitor cells. PMID: 7507245


  • a novel, genetically determined positive regulator of adult hematopoietic stem cell (HSCs). PMID: 14707111


  • expressed on CD34+ hematopoietic progenitor cells: a five dimensional flow cytometric study. PMID: 9718862

  • expressed on primitive cord blood progenitors with the highest in vitro proliferative potential, and further suggest that Thy-1 is involved in hematopoietic cell development, possibly by mediating a negative signal that results in inhibition of primitive cell proliferation. PMID: 7513197

  • Thy-1 antigen expression by murine high-proliferative capacity hematopoietic progenitor cells. I. Relation between sensitivity to depletion by Thy-1 antibody and stem cell generation potential. PMID: 6149245